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. 2021 Feb 4;11:3192. doi: 10.1038/s41598-021-82696-1

Table 2.

Differences in brain wave amplitude of several frequency bands between pain levels.

Pain levels to compare Frequency(Hz) P value
None vs Moderate 1 Hz 0.003
2 Hz 0.002
None vs Severe 5 Hz 0.005
6 Hz 0.008
11 Hz 0.036
12 Hz 0.016
13 Hz 0.008
14 Hz 0.007
15 Hz 0.011
16 Hz 0.031
18 Hz 0.034
24 Hz 0.050
Mild vs Moderate 1 Hz 0.001
2 Hz  < 0.001
Mild vs Severe 12 Hz 0.030
14 Hz 0.036
15 Hz 0.039
Moderate vs Severe 2 Hz  < 0.001
4 Hz 0.010
11 Hz 0.041
12 Hz 0.026
13 Hz 0.035

Amplitude power in each frequency was compared among quartile pain levels.

The amplitude power of 10 frequency bands was significantly different between pain levels “None” and “Severe”. Similarly, 2 bands, 3 bands, 2 bands and 5 bands were significantly different between pain levels “None” and “Moderate”, “Mild” and “Severe”, “Mild” and “Moderate” and “Moderate” and “Severe”, respectively. There were no significant between “None” and “Mild”.

Statistical analysis was undertaken using Student’s t-test and the resultant p values were corrected by Bonferroni correction to evaluate the significance.