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. 2021 Jan 22;11:522883. doi: 10.3389/fendo.2020.522883

Table 3.

Baseline characteristics in four groups with different TyG levels.

Variables Group 1 (n 232) Group 2 (n = 232) Group 3 (n = 232) Group 4 (n = 232) P-value
Baseline data
Male (n, %) 170 (73.3%) 162 (69.8%) 169 (72.8%) 157 (67.7%) 0.501
Age (years) 70.60 ± 9.15 69.01 ± 8.79 70.80 ± 7.81 63.21 ± 7.50 <0.001*
SBP (mmHg) 135.34 ± 20.04 135.49 ± 17.99 136.86 ± 16.00 140.83 ± 17.60 <0.001*
DBP (mmHg) 74.99 ± 10.43 74.25 ± 9.54 75.47 ± 13.74 81.87 ± 12.59 <0.001*
BMI (kg/m2) 25.44 ± 3.17 24.47 ± 5.70 24.03 ± 5.34 24.13 ± 4.62 0.260
Hypertension (n, %) 178 (72.4%) 184 (79.3%) 177 (72.0%) 202 (85.8%) 0.013
Hypotension (n, %) 2 (0.9%) 3 (1.3%) 5 (2.2%) 4 (1.7%) 0.694
Anemia (n, %) 4 (1.7%) 2 (0.9%) 1 (0.4%) 0 (0.0%) 0.169
CKD (n, %) 8 (3.4%) 4 (1.7%) 6 (2.6%) 1 (0.4%) 0.124
Hydration (n, %) 187 (80.8%) 191 (82.6%) 180 (77.6%) 178 (76.7%) 0.409
CI-AKI 7 (3%) 35 (15.1%) 66 (28.4%) 89 (38.4%) <0.001*
Coronary angiography
PCI (n, %) 165 (69.4%) 161 (66.8%) 166 (71.6%) 178 (76.7%) 0.112
Dose of contrast agent
P50 (P25–P75) (ml)
69 (45–83) 70 (50–92) 72 (50–92) 65 (50–92) 0.673
Number of lesion vessels 1.79 ± 0.64 1.65 ± 0.91 1.73 ± 0.54 1.52 ± 0.87 0.341
Number of stents 0.81 ± 0.34 1.02 ± 0.54 1.01 ± 0.48 0.92 ± 0.49 0.116
Hematological index
Preoperative eGFR P50
(P25–P75) (ml/min/1.73m2)
87.6 (78.7–92.4) 85.7 (75.5–89.0) 84.7 (77.5–86.9) 86.5 (80.6–88.3) 0.329
FBG P50 (P25–P75) (mmol/L) 6.12 (4.94–6.35) 7.08 (5.90–8.33) 7.93 (6.79–9.00) 8.47 (7.19–12.06) <0.001*
HbAlc (%) 7.60 ± 1.76 7.37 ± 1.46 7.47 ± 1.57 8.06 ± 1.60 <0.001*
Triglyceride P50
(P25–P75) (mmol/L)
0.69 (0.85–1.10) 1.16 (1.07–1.40) 1.68 (1.33–1.93) 2.74 (2.05–4.35) <0.001*
TC P50
(P25–P75) (mmol/L)
3.42 (3.00–3.74) 3.91 (3.32–4.4) 4.05 (2.66–5.06) 4.65 (3.93–5.54) <0.001*
HDL-c 1.18 (1.01–1.29) 1.11 (0.99–1.19) 1.09(0.98–1.13) 1.06 (0.93–1.10) 0.052
LDL-c 2.05 (1.46–2.26) 2.18 (1.83–2.77) 2.52 (1.37–3.06) 2.37 (1.72–3.28) <0.001*
TyG index 8.28 ± 0.29 8.83 ± 0.13 9.22 ± 0.13 10.05 ± 0.53 <0.001*
Medications
Oral hypoglycemic
Drugs (n, %)
203 (87.5%) 205 (88.4%) 212 (91.4%) 220 (94.8%) 0.030*
Insulin (n, %) 61 (26.3%) 63 (27.2%) 68 (29.3%) 72 (31.0%) 0.667
Aspirin 207 (89.2%) 211 (90.9%) 217 (93.5%) 215 (92.7%) 0.347
ACEI/ARB 140 (60.3%) 130 (56.0%) 134 (57.8%) 145 (62.5%) 0.506
β-blocker 195 (84.1%) 192 (82.8%) 205 (87.2%) 192 (82.8%) 0.29
CCB 115 (49.6%) 114 (49.1%) 123 (53.0%) 142 (61.2%) 0.033*
Statin 222 (95.7%) 230 (99.1%) 229 (98.7%) 227 (97.8%) 0.051

SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; CKD, chronic kidney dysfunction; CI-AKI, contrast induced-acute kidney injury; FPG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; TyG, triglyceride-glucose; eGFR, estimated glomerular filtration rate; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin II receptor blocker; CCB, calcium channel blocker.

* represents P < 0.05.