Figure 7.

Influence of Hsp60 in the virulence of H. capsulatum G186A (A) and EH-315 (B) strains using G mellonella as a model. Data are representative of three independent experiments. The groups of larvae infected with untreated yeasts are represented by the black dashed lines, larvae infected with yeasts treated with control IgG are represented by the black lines and the groups of larvae infected with yeasts treated with Hsp60 mAb 7B6 are represented by the gray lines. The pre-treatment of both H. capsultaum strains with Hsp60 mAb 7B6 significantly increased the survival of G. mellonella compared with non-treated yeasts and treated with unspecific IgG. *p < 0.05.