Table 1.
Gene ontology analysis (GO) for biological process (BP) was performed on genes downregulated in differentiated osteoblasts upon Rnf40 knockout.
| GO term | REFLIST | RNF40_DN n = 1248 | FDR |
|---|---|---|---|
| Endochondral bone morphogenesis (GO:0060350) | 73 | 23 | 3.58E−07 |
| Cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 49 | 18 | 2.84E−06 |
| Endochondral bone growth (GO:0003416) | 40 | 16 | 6.71E−06 |
| Bone growth (GO:0098868) | 43 | 16 | 1.27E−05 |
| Growth plate cartilage development (GO:0003417) | 33 | 14 | 2.25E−05 |
| Chondrocyte development (GO:0002063) | 41 | 15 | 3.34E−05 |
| Chondrocyte differentiation involved in endochondral bone morphogenesis (GO:0003413) | 29 | 13 | 3.46E−05 |
| Collagen fibril organization (GO:0030199) | 49 | 16 | 0.000045 |
| Growth plate cartilage chondrocyte differentiation (GO:0003418) | 22 | 11 | 0.00012 |
| Glutathione metabolic process (GO:0006749) | 49 | 15 | 0.000179 |