Figure 1.

A) Lollipop plot depicting 13 TP73 mutations found in 12 patients with newly diagnosed acute myeloid leukemia. Eleven patients each had a single TP73 mutation and one patient had two different TP73 mutations. The patient with dual mutations in both TP73 and TP53 is included. The structural domains of the gene are represented by color coding as outlined in the figure. Missense mutations are depicted by the blue circles. B) Lollipop plot depicting 98 mutations in the TP53 gene found in 88 patients with newly diagnosed acute myeloid leukemia. The patient with dual mutations in both TP73 and TP53 is included. The structural domains of the gene are represented by color coding as outlined in the figure. Frameshift mutations are depicted by the red circles, nonsense mutations are depicted by the orange circles, missense mutations are depicted by the blue circles, and indel mutations are depicted by the gray circles. The numbers within each circle denote the numbers of mutations at certain sites within the gene.