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. 2021 Feb 4;11:3048. doi: 10.1038/s41598-021-82733-z

Table 2.

Univariate analysis results, 17 proteins were significantly different in preeclampsia vs controls after false discovery rate correction (q-value < 0.05).

Uniprot Protein name (gene name) Controls
Mean (SD)
Preeclampsia
Mean (SD)
p-value q-value Preeclampsia/controls
P06681 Complement C2 (C2) 0.500 (0.245) − 0.214 (0.247) < 0.0001 0.0008 Down
Q9UGM5 Fetuin-B (FETUB) 0.649 (0.175) − 0.278 (0.479) < 0.0001 0.0008 Down
P02774 Vitamin D-binding protein (GC) 0.551 (0.128) − 0.236 (0.492) < 0.0001 0.0020 Down
P02751 Fibronectin type III domain containing (FN1) − 0.766 (0.419) 0.328 (0.426) < 0.0001 0.0020 Up
Q06033 Inter-alpha-trypsin inhibitor heavy chain H3 (ITIH3) − 0.692 (0.463) 0.297 (0.399) 0.0001 0.0030 Up
P04275 Von Willebrand factor (VWF) − 0.783 (0.467) 0.336 (0.483) 0.0001 0.0030 Up
P08185 Corticosteroid-binding globulin (SERPINA6) 0.744 (0.289) − 0.319 (0.482) < 0.0001 0.0030 Down
O75636 Ficolin-3 (FCN3) 0.626 (0.345) − 0.268 (0.398) 0.0002 0.0030 Down
P19823 Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2) − 0.550 (0.255) 0.236 (0.348) 0.0004 0.0063 Up
P22352 Glutathione peroxidase 3 (GPX3) − 0.658 (0.327) 0.282 (0.491) 0.0005 0.0073 Up
P01042 Kininogen-1 (KNG1) 0.472 (0.306) − 0.202 (0.385) 0.0013 0.0192 Down
P19827 Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) − 0.442 (0.193) 0.189 (0.393) 0.0016 0.0215 Up
P27918 Properdin (CFP) 0.553 (0.228) − 0.237 (0.505) 0.0019 0.0231 Down
P01024 Complement C3 (C3) 0.391 (0.208) − 0.168 (0.362) 0.0025 0.0286 Down
P02760 Protein AMBP (AMBP) − 0.487 (0.273) 0.209 (0.519) 0.0046 0.0431 Up
P00740 Coagulation factor IX (F9) SERPIND1 − 0.336 (0.185) 0.144 (0.436) 0.0046 0.0431 Up
P60709 Actin, cytoplasmic 1 (ACTB) − 0.632 (0.516) 0.271 (0.589) 0.0044 0.0431 Up