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. 2021 Jan 22;14:598453. doi: 10.3389/fncel.2020.598453

Figure 24.

Figure 24

Overview of the molecular signaling pathway. It is involved in LPS-preconditioned cells, LPS-induced cells, and LPS-induced cells incubated with caspase inhibitors via TLR4/caspase-3/NF-κB signaling pathway in differentiated PC12 cells. Transcriptional factor NF-κB and caspase-3 are associated with cytoprotection, inflammation, and activation of oncogene expressions.