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. 2021 Jan 22;13:574041. doi: 10.3389/fnmol.2020.574041

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Copyright © 2021 Liu, Li, Huang, Lin, Ji, Huang, Liu, Wu, Wu, Jiang, Ye and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The representative Western blot images and the histogram showed the relative expression of Beclin-1, LC3BII, and p62. Representative Western blots and quantitative graphs demonstrate that the expression of Beclin-1 in the rapamycin-treated group was significantly greater than that in the vehicle and sham groups (A,B), the expression of p62 decreased significantly in the two injured groups compared with the sham group after spinal cord injury (SCI) (C,D), and the expression of LC3BII in the rapamycin group was significantly greater than that in the vehicle and sham groups (E,F). Rapa, the rapamycin group; Veh, The vehicle group; Sham, the sham group. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, ^nsP > 0.05. Error bars are mean ± SEM.