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. 2021 Jan 22;13:574041. doi: 10.3389/fnmol.2020.574041

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Copyright © 2021 Liu, Li, Huang, Lin, Ji, Huang, Liu, Wu, Wu, Jiang, Ye and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The changes in behavioral scores and body weight with time. (A) Rearing scores showed that rapamycin can increased the usage rate of the ipsilateral forelimb after spinal cord injury (SCI). (B) Grooming scores showed that the function of elbow and shoulder on the ipsilateral side was not improved by rapamycin after SCI. (C) The administration of rapamycin decreased body weight gain after injury. Rapa, the rapamycin group; Veh, the vehicle group; Sham, the sham group; WPI, weeks post-injury. ^∗P < 0.05, ^∗∗∗P < 0.001, ^*⁣*⁣**P < 0.0001. Error bars are mean ± SEM.