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. 2021 Feb 4;11:3086. doi: 10.1038/s41598-021-82587-5

Table 4.

Correlation of resting fMRI data with neurocognitive variables.

NP domains Type of resting fMRI data Brain regions Peak p (uncorr) Number of cluster voxels MNI coordinate (mm)
x
MNI coordinate (mm)
y
MNI coordinate (mm)
x
Peak
t
Figure
Social cognition ALFF Left cerebral white matter/left medial orbital gyrus 0.000 (−ve) 3 22 48 − 18 6.02 Figure 1B
Left cerebral white matter 0.001 (−ve) 3 − 50 4 − 12 4.26 Figure 1B
Left cerebral white matter 0.002 (−ve) 7 − 32 36 20 3.84 Figure 1B
ReHo Right cerebral white matter 0.000 (−ve) 5 12 28 − 10 5.41 Figure 2A
ReHo Right central operculum /right cerebral white matter 0.002 (+ve) 4 48 0 − 4 3.71 Figure 2A
Psychomotor functions ALFF Right cerebral white matter/right medial orbital gyrus 0.002 (−ve) 4 18 40 − 18 3.97 Figure 1A
Abstract thinking ALFF Right cerebral white matter 0.001 (−ve) 3 14 56 − 16 4.77 Figure 1A
ReHo Right cerebral white matter 0.006 (−ve) 5 18 44 − 12 3.18 Figure 2A

Brain regions masked with significantly higher regional neuronal activity in the pediatric HIV group compared to healthy controls, showed mostly negative correlation (peak uncorrected p  <  0.01, cluster size ≥ 3) of Social Cognition, negative correlation of Psychomotor Functioning and negative correlation of Abstract Thinking with regional neuronal activity in the 11 pediatric HIV patients. + ve indicate positive correlation and − ve indicate negative correlation.