Table 4.
NP domains | Type of resting fMRI data | Brain regions | Peak p (uncorr) | Number of cluster voxels | MNI coordinate (mm) x |
MNI coordinate (mm) y |
MNI coordinate (mm) x |
Peak t |
Figure |
---|---|---|---|---|---|---|---|---|---|
Social cognition | ALFF | Left cerebral white matter/left medial orbital gyrus | 0.000 (−ve) | 3 | 22 | 48 | − 18 | 6.02 | Figure 1B |
Left cerebral white matter | 0.001 (−ve) | 3 | − 50 | 4 | − 12 | 4.26 | Figure 1B | ||
Left cerebral white matter | 0.002 (−ve) | 7 | − 32 | 36 | 20 | 3.84 | Figure 1B | ||
ReHo | Right cerebral white matter | 0.000 (−ve) | 5 | 12 | 28 | − 10 | 5.41 | Figure 2A | |
ReHo | Right central operculum /right cerebral white matter | 0.002 (+ve) | 4 | 48 | 0 | − 4 | 3.71 | Figure 2A | |
Psychomotor functions | ALFF | Right cerebral white matter/right medial orbital gyrus | 0.002 (−ve) | 4 | 18 | 40 | − 18 | 3.97 | Figure 1A |
Abstract thinking | ALFF | Right cerebral white matter | 0.001 (−ve) | 3 | 14 | 56 | − 16 | 4.77 | Figure 1A |
ReHo | Right cerebral white matter | 0.006 (−ve) | 5 | 18 | 44 | − 12 | 3.18 | Figure 2A |
Brain regions masked with significantly higher regional neuronal activity in the pediatric HIV group compared to healthy controls, showed mostly negative correlation (peak uncorrected p < 0.01, cluster size ≥ 3) of Social Cognition, negative correlation of Psychomotor Functioning and negative correlation of Abstract Thinking with regional neuronal activity in the 11 pediatric HIV patients. + ve indicate positive correlation and − ve indicate negative correlation.