Table 3.
GAGE analysis for AA, DHA, and EPA derived metabolite pathway changes over the indicated time periods.
| Lipid derived pathway | Time period | Non-centrifuged CSF | CSF cell pellet | CSF supernatant | |||
|---|---|---|---|---|---|---|---|
| p-value | q-value | p-value | q-value | p-value | q-value | ||
| AA | Before surgery to 24 h after surgery | 0.373 | 0.851 | 0.0000247 | 0.0000741 | 0.0155 | 0.0464 |
| Before surgery to 6 weeks after surgery | 0.497 | 0.778 | 0.0000497 | 0.000149 | 0.00239 | 0.00716 | |
| 24 h after surgery to 6 weeks after surgery | 0.200 | 0.601 | 0.0000499 | 0.000150 | 0.00363 | 0.0109 | |
| DHA | Before surgery to 24 h after surgery | 0.567 | 0.567 | 1.00 | 1.00 | 0.922 | 1.00 |
| Before surgery to 6 weeks after surgery | 0.519 | 0.778 | 1.00 | 1.00 | 0.973 | 1.00 | |
| 24 h after surgery to 6 weeks after surgery | 0.723 | 1.00 | 1.00 | 1.00 | 0.978 | 1.00 | |
| EPA | Before surgery to 24 h after surgery | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Before surgery to 6 weeks after surgery | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
| 24 h after surgery to 6 weeks after surgery | 1.00 | 1.00 | 0.999 | 1.00 | 1.00 | 1.00 | |