Skip to main content
. 2021 Feb 4;12:793. doi: 10.1038/s41467-021-21039-0

Fig. 7. The binding of Zα to AluSx1Jo is more dynamic than to (CpG)3 RNA.

Fig. 7

a Residues for which CPMG data and exchange rates (kex) were obtained between the free and the bound complex at 2:1 Zα:RNA are shown on surface plots of Zα bound to (CpG)3 DNA (left, PDB: 3F2147, kex rates from23), to (CpG)3 RNA (right, PDB: 2GXB25, kex rates from23), and for the AluSx1Jo RNA (middle, plotted on PDB: 2GXB25; residue-specific CPMG parameters for the AluSx1Jo are given in Supplementary Table 2 and fits are shown in Supplementary Fig. 16). b Globally fitted kex values for Zα binding to, from left to right, (CpG)3 DNA23 (all residues or only binding-site residues kex values are given), the AluSx1Jo RNA (globally fitted CPMG parameters are given in Supplementary Table 3), and (CpG)3 RNA23.