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. 2021 Feb 1;12(2):139. doi: 10.1038/s41419-021-03431-2

Fig. 8. Ischemia-reperfusion-induced acute kidney injury was attenuated in GSDME deletion mice.

Fig. 8

GSDME KO and WT mice (8–12 weeks) underwent renal ischemia-reperfusion or the same procedure, without renal vessel occlusion (Sham group, n = 5; IR group, n = 7). a, b Serum Cr and BUN levels of mice. c HE staining of kidney sections (scale bar = 20 μm). d Renal tubular injury score of mice. e Renal protein level of NGAL. f Quantitative analysis of NGAL protein level from western blotting. g Renal protein level of KIM-1. h Quantitative analysis of KIM-1 protein level from western blotting. i Transcriptional levels of KIM-1 in mouse kidney. *P < 0.05, **P < 0.01, and ***P < 0.001.