Table 1. Characteristics of a Cohort of 15 637 Transgender Adults and a Cohort of 46 911 Cisgender Adults in the US, 2017.
| Characteristic | No. (%) | Bivariate comparisonsa | ||
|---|---|---|---|---|
| Transgender (n = 15 637) | Cisgender (n = 46 911) | χ2 | P value | |
| Geographic regionb | ||||
| Northeast | 1963 (12.6) | 5889 (12.6) | NA | NA |
| Midwest | 3760 (24.0) | 11 280 (24.0) | ||
| West | 3432 (21.9) | 10 296 (21.9) | ||
| South | 6482 (41.5) | 19 446 (41.5) | ||
| Age, y | ||||
| 18-25 | 4084 (26.1) | 12 252 (26.1) | NA | NA |
| 26-30 | 1858 (11.9) | 5574 (11.9) | ||
| 31-35 | 1369 (8.8) | 4107 (8.8) | ||
| 36-40 | 1316 (8.4) | 3948 (8.4) | ||
| 41-45 | 1167 (7.5) | 3501 (7.5) | ||
| 45-50 | 1302 (8.3) | 3906 (8.3) | ||
| 51-55 | 1257 (8.0) | 3771 (8.0) | ||
| 56-60 | 1154 (7.4) | 3462 (7.4) | ||
| ≥61 | 2130 (13.6) | 6390 (13.6) | ||
| Gender spectrum | ||||
| Transfeminine | 2079 (13.3) | NA | NA | NA |
| Transmasculine | 4955 (31.7) | NA | ||
| Unknown gender | 8603 (55.0) | NA | ||
| Male | NA | 23 664 (50.4) | ||
| Female | NA | 23 247 (49.6) | ||
| SUDDs | ||||
| Polysubstance | 310 (2.0) | 245 (0.5) | 284.3 | <.001 |
| Nicotine | 2594 (16.6) | 2551 (5.4) | 1931.7 | <.001 |
| Alcohol and drug | 887 (5.7) | 820 (1.7) | 680.4 | <.001 |
| Alcohol | 401 (2.6) | 438 (0.9) | 235.7 | <.001 |
| Drug | 678 (4.3) | 549 (1.2) | 611.1 | <.001 |
| Cannabis | 321 (2.1) | 186 (0.4) | 400.2 | <.001 |
| Cocaine | 81 (0.5) | 59 (0.1) | 80.8 | <.001 |
| Opioid | 205 (1.3) | 207 (0.4) | 135.6 | <.001 |
| Another drugc | 265 (1.7) | 183 (0.4) | 280.7 | <.001 |
Abbreviations: NA, not applicable; SUDD, substance use disorder diagnoses.
a
Bivariate comparisons are not reported for age and geographic region because the cisgender cohort was matched 3 to 1 to the transgender cohort based on these characteristics.
b
Hawaii and Alaska are included in the West according to the US Census. US territories (eg, Puerto Rico and Guam) are not included in US Census regions; thus the approximately 100 individuals without an assigned census region were included in the South.
c
Another drug SUDD includes hallucinogens, sedatives, stimulants, and the diagnosis of other SUD not otherwise specified.