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. 2021 Feb 4;139(3):330–337. doi: 10.1001/jamaophthalmol.2020.6525

Table 4. Comparison of Rates of Change in Retinal Thickness Between Patients With Stage-Progressed vs Non–Stage-Progressed Sickle Cell Retinopathy Measured by Spectral-Domain Optical Coherence Tomography.

ETDRS subfield Rate of change in eyes with nonprogressed retinopathy, μm/y Difference in rate of change in eyes with progressed vs nonprogressed retinopathy (95% CI), μm/y P value
Central −0.18 −0.03 (−0.47 to 0.41) .89
Inner
Nasal −0.99 0.30 (−0.11 to 0.72) .15
Superior −1.39 0.01 (−0.54 to 0.56) .97
Temporal −0.75 −0.81 (−1.32 to −0.30) .002
Inferior −0.85 −0.12 (−0.55 to 0.31) .59
Outer
Nasal −1.00 0.79 (0.43 to 1.15) <.001
Superior −0.25 −0.02 (−1.07 to 1.04) .98
Temporal −0.97 −0.14 (−0.98 to 0.69) .73
Inferior −1.10 0.59 (0.10 to 1.07) .02

Abbreviation: ETDRS, Early-Treatment Diabetic Retinopathy Study.