Table 1.
Summary of Gross Pathologic Findings
| Age of Mice | Ear tumors, n/N (%) |
Tail tumors, n/N (%) |
Limb tumors, n/N (%) |
Splenomegaly, n/N (%) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | Tax+ | Tax+/IFN-γ−/− | WT | Tax+ | Tax+/IFN-γ−/− | WT | Tax+ | Tax+/IFN-γ−/− | WT | Tax+ | Tax+/IFN-γ−/− | |
| 6 months | 0/6 (0) | 0/3 (0) | 3/10 (30) | 0/6 (0) | 1/3 (33) | 7/10 (70) | 0/6 (0) | 1/3 (33) | 6/10 (60) | 0/6 (0) | 0/3 (0) | 3/10 (30) |
| 9 months | 0/4 (0) | 1/4 (25) | 6/10 (60) | 0/4 (0) | 1/4 (25) | 7/10 (70) | 0/4 (0) | 1/4 (25) | 3/10 (30) | 0/4 (0) | 2/4 (50) | 7/10 (70) |
| 12 months | 0/12 (0) | 0/6 (0) | 8/10 (80) | 0/12 (0) | 0/6 (0) | 9/10 (90) | 0/12 (0) | 0/6 (0) | 1/10 (10) | 1/12 (8) | 4/6 (66) | 3/10 (30) |
| 15 months | 0/6 (0) | 1/9 (11) | N/A | 0/6 (0) | 2/9 (22) | N/A | 0/6 (0) | 0/9 (0) | N/A | 0/6 (0) | 3/9 (33) | N/A |
N/A, not available.