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. 2021 Feb 2;5(1):2473974X21991449. doi: 10.1177/2473974X21991449

Table 1.

Treatment Outcomes in Patients Receiving Anti-IL-5 Therapy. a

Effusion b Eosinophils c Audiology d
Patient Drug No. of injections Before After Before After Before After Side effects
1 Mepolizumab 30 Yes No 80 Moderate, conductive Mild-moderate, conductive None
2 Benralizumab 8 Yes No 600 0 None
3 Mepolizumab 27 Yes Yes 1141 0 None
4 Mepolizumab 6 No No 391 Moderate SNHL None
5 Mepolizumab 21 Yes No 454 100 Moderate SNHL Fatigue, myalgias
6 Mepolizumab 12 Yes No 657 Moderate, conductive Mild, conductive None
7 Mepolizumab Unclear Yes Yes 370 0 None
8 Benralizumab 8 Yes No 200 0 Moderate, conductive Moderate, conductive None
9 Mepolizumab 15 No No 1137 None

Abbreviation: SNHL, sensorineural hearing loss.

a

Blank cells indicate not applicable.

b

Presence of middle ear effusion before and after starting anti-IL-5 therapy.

c

Absolute number of eosinophils present in serum before and after starting anti-IL-5 therapy.

d

Hearing loss based on audiologic results before and after starting anti-IL-5 therapy.