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. 2021 Feb 4;17:68. doi: 10.1186/s12917-021-02773-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Representative photomicrograph of the low (40X) and high (400X) magnification H&E stained duodenums segment sections showing short and thick villi with limitation goblet cell metaplasia besides increasing inflammatory cells in the lamina propria in 0Vit.C+ 0Saff. Oil group; tall and thin villi with a few broad tips in a few villi without goblet cell metaplasia in 0Vit.C + 5 Saff. Oil group; marked brad tips and serrated surfaces with marked goblet cell metaplasia besides mild adhesions in 0Vit.C+ 10Saff. Oil group; more healthy which characterized by gradual increase tall and thin villi without goblet cells metaplasia in each 400Vit.C + 0Saff. Oil, 400Vit.C + 5Saff. Oil, and 400Vit.C + 10Saff. Oil groups respectively except increase intra-epithelium lymphocytic lick cells infiltrations in 400Vit.C+ 10Saff. Oil group. (a and a: 0Vit.C+ 0Saff. Oil group, b, and b: 0Vit.C + 5 Saff. Oil group, c, and c:0Vit.C+ 10Saff. Oil group: d and d: 400Vit.C + 0Saff. Oil, e and e: 400Vit.C + 5Saff. Oil, f and f: 400Vit.C+ 10Saff. Oil group)