Table 6.
Average c-index values of the proposed model and random forest model using different numbers of randomly selected signaling pathways. The mean c-index was obtained by randomly selecting the training (80% of the dataset) and test (20% of dataset) data for 50 times
# of pathway | Proposed model | Random forest model | ||
---|---|---|---|---|
Mean c_index on training data | Mean c_index on test data | Mean c_index on training data | Mean c_index on test data | |
GBM | ||||
10 | 0.6428 | 0.6115 | 0.6832 | 0.5182 |
20 | 0.6442 | 0.6129 | 0.672 | 0.5159 |
30 | 0.6247 | 0.5975 | 0.6617 | 0.5314 |
40 | 0.6300 | 0.6196 | 0.6602 | 0.5418 |
SKCM | ||||
10 | 0.6948 | 0.6626 | 0.7684 | 0.4943 |
20 | 0.7226 | 0.6702 | 0.7701 | 0.4434 |
30 | 0.7197 | 0.6614 | 0.772 | 0.4336 |
40 | 0.7629 | 0.6772 | 0.7739 | 0.4265 |
BRCA | ||||
10 | 0.4397 | 0.3713 | 0.7859 | 0.5294 |
20 | 0.6051 | 0.4577 | 0.8029 | 0.5225 |
30 | 0.6661 | 0.5622 | 0.81 | 0.5282 |
40 | 0.6497 | 0.5506 | 0.8093 | 0.5139 |
LUAD | ||||
10 | 0.7349 | 0.7050 | 0.8158 | 0.5195 |
20 | 0.7226 | 0.7131 | 0.8162 | 0.5349 |
30 | 0.7347 | 0.7171 | 0.8101 | 0.5551 |
40 | 0.7119 | 0.7226 | 0.8091 | 0.5669 |