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. 2021 Feb 5;21:65. doi: 10.1186/s12887-021-02507-4

Table 3.

Comparison of clinical characteristics of the severe and mild cases

Severe cases
(n = 22)
Mild cases
(n = 162)
Gender
Male 12 90
Female 10 72
Age (months)* 2.80 ± 1.26 4.97 ± 4.30
< 3 months * 14 (63.64%) 63 (38.89%)
Not vaccinated with pertussis vaccine* 22 (100%) 98 (60.49%)
Prematurity 4(18.18%) 19(11.73%)
Low birth weight 1(4.55%) 20(12.35%)
Macrosomia 2(9.09%) 8(4.94%)
Congenital heart disease 0 5(3.09%)
Fever* 19 (86.36%) 34 (20.99%)
Severe pneumonia 22 (100%) 0
Elevated neutrophilia percentage * 15 (68.18%) 10 (6.17%)
Elevated C-reactive protein* 11 (50.00%) 20 (12.33%)
CRP value (mg/L)* 22.37±48.89 1.52±2.13
Elevated procalcitonin * 9 (40.91%)) 2 (1.23%)
PCT value (ng/ml)* 1.88±4.69 0.08±0.10
Positive bacterial sputum culture* 8 (36.36%) 15 (9.26%)
Leukocyte count (× 109/L)* 35.80 ± 20.53 19.41 ± 8.59
Leukocyte count > 50× 109/L* 4 (18.18%) 0
Antibiotic usage
 Three or more antibiotics* 18 (81.82%) 8 (4.94%)
 Special-grade antibiotics* 15 (68.18%) 4 (2.47%)
Length of hospitalization (days)* 27.71 ± 11.19 14.56 ± 5.84
Cases of death 4(18.18%) 0

*p<0.05, comparison between moderate and severe cases using statistical methods.