Table 2.
The effect of Otostegia integrifolia extract on systolic blood pressure in fructose induced hypertensive rat
| Group | Systolic BP | |||
|---|---|---|---|---|
| Day 0 | Day 5 | Day 10 | Day 15 | |
| DF66 | 118.66 + 4.8 | 185.16 + 6.68 | 161 + 9.25 | 151.58 + 4.02 |
| CAP20 | 108.41+ 2.45 | 98.66 + 4.81 b3c3d3e3 | 96.33 + 7.91 b3c1 | 93.00 + 5.31 b3 |
| OI250 | 116.16+ 3.49 | 150.66 + 8.79 a2 | 135 + 13.17 | 109.75 + 11.64 a3 |
| OI500 | 121.91+ 4.76 | 140 + 6.26 a3 | 87.08 + 9.24 a3 f2 | 109.33 + 3.08 a3 |
| OI1000 | 110.25+ 6.13 | 142.41 + 3.17a3 | 96.91 + 4.51 a3 f1 | 102.91 + 4.17 a3 |
Data are expressed as mean ± SEM (n = 6); Analysis was performed by one-way ANOVA; a, DF66 vs OI; b, DF66 vs CAP20; c, OI250 vs CAP20; d, OI500 vs CAP20; e, OI1000 vs CAP20; f, OI250 vs OI500 and OI100; DF66 Rats with 66% fructose ingestion, CAP20 Captopril 20 mg/kg, OI Otostegia integrifolia at doses of 250, 500 and 1000 mg/kg; 1p < 0.05; 2p < 0.01; 3p < 0.001.