Table 3.
The effect of Otostegia integrifolia extract on diastolic blood pressure in fructose induced hypertensive rat
| Group | Diastolic BP | |||
|---|---|---|---|---|
| Day 0 | Day 5 | Day 10 | Day 15 | |
| DF66 | 89.66 + 5.03 | 164.54 + 6.69 | 144.62 + 10.84 | 143.58 + 4.02 |
| CAP20 | 88.54 + 4.86 | 74.91 + 3.85 b3c3d3e3 | 69.87 + 8.07 b3 c1 | 65.25 + 3.94 b3 |
| OI250 | 82.54 + 2.43 | 132.34 + 10.16 a1 | 119.25 + 10.83 | 86.50 + 11.58a3 |
| OI500 | 90.91 + 6.14 | 118.61 + 6.78 a3 | 65.08 + 9.24 a3 f2 | 87.33 + 2.77 a3 |
| OI1000 | 86.33 + 5.70 | 127.75 + 5.37 a2 | 72.79 + 8.00 a3 f1 | 85.54 + 5.34 a3 |
Data are expressed as mean ± SEM (n = 6); Analysis was performed by one-way ANOVA; a, DF66 vs OI; b, DF66 vs CAP20; c, OI250 vs CAP20; d, OI500 vs CAP20; e, OI1000 vs CAP20; f, OI250 vs OI500 and OI100; DF66 Rats with fructose ingestion, CAP20 Captopril 20 mg/kg; OI, Otostegia integrifolia at doses of 250, 500 and 1000 mg/kg; 1p < 0.05; 2p < 0.01; 3p < 0.001.