Figure 2. Syne4 −/− hair cells mature normally and then degenerate between P12 and P14.

- Whole‐mount immunofluorescence of a P8 Syne4 −/− organ of Corti showing intact hair cells, as labeled with myosin VIIa.
- Whole‐mount immunofluorescence of WT and Syne4 −/− organ of Corti from the 8, 16, and 32 kHz regions at P8 and P14.
- Inner and outer hair cell counts of Syne4 −/− organ of Corti at P8, P10, P12, and P14.
- FM1‐43 uptake performed on P8+1 DIV (days‐in‐vitro) WT and Syne4 −/− organ of Corti. Top shows OHC plane, and bottom shows IHC plane.
Data information: Scale bars = 100 μm for (A) and 10 μm for (B and D).
Source data are available online for this figure.