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. 2020 Dec 28;13(2):e12710. doi: 10.15252/emmm.202012710

Figure EV5. miR‐574‐FAM210A axis modulates mitochondrial protein expression and mitochondrial activity in murine hearts.

Figure EV5

  • A, B
    IF analysis of protein expression of ETC complex protein components in WT and miR‐574 KO hearts 3 days after TAC surgery. n = 5 hearts per group with> 100 CMs measured per group. Scale bar: 10 μm. The dashed line in the violin plot shows medium value for the group and the dotted lines represent two quartile lines in each group.
  • C
    Measurement of mitochondrial copy number in WT and miR‐574 KO hearts 3 days after TAC surgery (n = 4).
  • D
    Measurement of mitochondrial electron transport chain complex enzymatic activities in heart lysates of WT and miR‐574 KO mice at 4 weeks after TAC or Sham surgery (n = 5 per group).

Data information: Data were presented as mean ± SEM. P values were calculated by two‐way ANOVA with Tukey’s multiple comparisons test (B‐D).

Source data are available online for this figure.