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. 2021 Feb 5;19:42. doi: 10.1186/s12916-020-01896-0

Table 2.

Neurodevelopmental outcome at 12 months corrected age and 36 months chronological age

Standard care Early intervention p value
12 months follow-up n = 15 n = 17
 General quotient, mean ± SD 90.5 ± 3.3 93.9 ± 4.4 0.017^
 Locomotor, mean ± SD 96.3 ± 5.7 94.9 ± 9.8 0.894*
 Personal-social, mean ± SD 87.5 ± 4.6 93.9 ± 5.1 0.001^
 Hearing and language, mean ± SD 91.0 ± 4.2 94.8 ± 3.8 0.024*
 Eye and hand coordination, mean ± SD 89.5 ± 6.2 94.7 ± 4.8 0.014^
 Performance, mean ± SD 91.1 ± 3.9 94.8 ± 5.6 0.026*
36 months follow-up n = 15 n = 14
 General quotient, mean ± SD 86.5 ± 4.7 90.7 ± 4.8 0.026^
 Locomotor, mean ± SD 91.3 ± 4.0 91.9 ± 5.5 0.744^
 Personal-social, mean ± SD 85.0 ± 5.3 89.8 ± 4.1 0.009*
 Hearing and language, mean ± SD 86.1 ± 7.4 92.3 ± 5.2 0.014^
 Eye and hand coordination, mean ± SD 86.8 ± 5.9 92.4 ± 4.7 0.009^
 Foundation of learninga, mean ± SD 89.0 ± 5.3 93.7 ± 3.4 0.008^

Means ± standard deviations are shown. P values were obtained using t test (^) or Mann-Whitney U test (*). aThis subscale corresponds to “Performance” in GMDS-R