Table 4.
Gelatin Composite Scaffolds.
Biomaterial | Fabrication method | Cell(s) | Performance | Ref. |
---|---|---|---|---|
Gelatin–PCL | Core-shell electrospinning + EDC crosslinking | HDF, HEK | Promotes cell adhesion and metabolism as well as dermal/epidermal layer stratification to a level equivalent to pure gelatin fibers while offering significantly improved mechanical properties | [233] |
Gelatin–PCL | Electrospinning (non-crosslinked) | GFP-mouse fibroblast, HaCaT cells | Phase separation during electrospinning affects the GFP-mouse fibroblasts and HaCaT cells adhesion and proliferation | [235] |
Gelatin–dextran, PCL–Poloxamer (bilayer) | Gelation, Electrospinning | ADSCs | The bilayer scaffold supports cell viability | [236] |
GelMA | Cell-laden + UV crosslinking | HaCaT | Controlling hydrogel stiffness, improved degradation, stratification of keratinocytes, decreased water loss rate and enhanced electrical resistance vs collagen scaffold | [116] |