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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: FASEB J. 2021 Feb;35(2):e21335. doi: 10.1096/fj.202002257R

Fig. 4. ES-2 tumor stimulates the discrepant expression of Pol I subunits.

Fig. 4.

Expression of the Pol I-subunits Polr1a, Polr1b, Polr1c, Polr1d, PAF53, PAF49, Twistnb, Polr2e, and Polr2k was significantly elevated, whereas Znrd1, Polr2f, Polr2h, Polr2l was downregulated with ES-2 tumor. Insert: Heatmap illustrating the relative expression of Pol I subunits. Polr1a: RNA Polymerase I Subunit A, Polr1b: RNA Polymerase I Subunit B, Polr1c: RNA Polymerase I Subunit C, Polr1d: RNA Polymerase I Subunit D, Znrd1: Zinc Ribbon Domain Containing 1, PAF53 (Polr1e): RNA polymerase I associated factor 53, PAF49: RNA polymerase I associated factor 49, Twistnb (Polr1f): TWIST Neighbor, Polr2e-f: RNA polymerase II subunit E-F. Values are mean ± SD. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001 vs. control.