Figure 4.

Kaplan–Meier curve of the incidence of a combined kidney end point (start of KRT, incidence of eGFR<15 ml/min per 1.73 m² or eGFR decrease >40%) in the overall DIPAK cohort (n=706), according to tertiles of baseline urine-to-plasma urea ratio. The upper tertile (>31.6, tertile 3 [T3]) is depicted with a solid line, the middle tertile (19.7–31.6, tertile 2 [T2]) with a dashed line, and the lowest tertile (<19.7, tertile 1 [T1]) with a dotted line. Compared with the upper tertile, the second tertile had a hazard ratio of 6.76 (95% confidence interval, 3.35 to 13.7; P<0.001) and the first tertile had a hazard ratio of 13.1 (95% confidence interval, 6.55 to 26.1; P<0.001).