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DNA adsorbs on the surface of NPs. (a) A fluorescence assay (AccuClear Nano) was used to measure the concentration of DNA adsorbed on amine- (NP+) and carboxylate- (NP−) modified NPs (200 nm). Experiments were carried out in triplicate and error bars show standard deviation. ****p < 0.0001. (b) Gel electrophoresis shows the DNA adsorbed on the NP surface. NPs are visible in the wells due to staining of the NPs by EtBr. Equal concentrations of NP+ and NP− were loaded for all experiments.
