Table 1.
Baseline Characteristics for 5,585 Lung Transplant Recipients With COPD
| Characteristics | Righ single lung transplantation | Left single lung transplantation | Double lung transplantation | p-value |
|---|---|---|---|---|
| Number of transplant recipients | 995 | 1,010 | 3,580 | — |
| Age, years, median (IQR) | 63 (59–65) | 63 (59–66) | 60 (55–64) | <0.001 |
| Female, % | 53.6 | 48.8 | 45.7 | <0.001 |
| Race/ethnicity, % | ||||
| White | 92.9 | 92.2 | 90.9 | 0.41 |
| Black | 5.2 | 6.2 | 7.0 | |
| Hispanic | 1.2 | 0.9 | 1.1 | |
| Other | 0.7 | 0.7 | 1.0 | |
| BMI at listing, median (IQR) | 24.4 (21.3–27.5) | 24.6 (21.7–27.8) | 24.3 (21.3–27.4) | 0.14 |
| ABO blood type, % | ||||
| O | 41.3 | 42.7 | 42.2 | 0.092 |
| A | 45.7 | 43.6 | 41.6 | |
| B | 9.0 | 9.4 | 11.3 | |
| AB | 3.9 | 4.4 | 4.9 | |
| LAS at transplantation, median (IQR) | 33.4 (32.4–34.8) | 33.2 (32.4–34.6) | 33.6 (32.6–35.4) | <0.001 |
| O2 requirement at transplantation in liters of O2, median (IQR) | 3 (2–4) | 3 (2–4) | 3(2–4) | <0.001 |
| Mean PAP ≥ 40, % | 3.2 | 2.2 | 6.1 | <0.001 |
| ECMO before transplantation, % | 0.1 | 0.0 | 0.5 | 0.014 |
| Ventilator before transplantation, % | 1.7 | 2.2 | 3.4 | 0.006 |
| Donor age, years, median (IQR) | 32(22–47) | 30 (21–44) | 33 (23–48) | <0.001 |
| Gender mismatch between donor and recipient, % | 32.5 | 32.3 | 29.1 | 0.037 |
| Ischemic time, hours, median (IQR) | 3.9 (3.1–4.7) | 3.8 (3.0–4.6) | 5.3 (4.3–6.3) | <0.001 |
| 6-minute walk distance, feet, median (IQR) | 760 (512–965) | 738 (520–960) | 780(514.5–1,008) | 0.008 |
| pTLC ratio ≥1.1, % | 33.8 | 35.7 | 29.7 | <0.001 |
| Transplantation center volume, median (IQR) | 42.9 (21–56) | 43.3 (23–68) | 50.8 (29–74) | p < 0.001 |
| Creatinine before transplantation, median (IQR) | 0.8 (0.66–0.91) | 0.8 (0.69–0.99) | 0.8 (0.66–0.91) | 0.009 |
| Donor smoking of >20 pack per years, % | 9.2 | 8.8 | 10.0 | 0.61 |
Abbreviations: BMI, body mass index; COPD, chronic obstructive pulmonary disease; ECMO, extracorporeal membrane oxygenation; IQR, interquartile range; LAS, lung allocation score; O2, oxygen; PAP, pulmonary artery pressure; pTLC, predicted total lung capacity.