. Author manuscript; available in PMC: 2021 Feb 5.

Published in final edited form as: J Heart Lung Transplant. 2020 Jun 24;39(9):870–877. doi: 10.1016/j.healun.2020.06.009

Table 3.

Sub-group Analysis

Characteristics	Right single transplantation	Left single transplantation	Double lung transplantation

Early era
May 2005-June 30, 2010
n	511	481	1,332
Adjusted HR^a (95% CI)	1	1.23 (1.04–1.45), p = 0.016	0.86 (0.72–1.03), p = 0.101
Late era
June 2010-June 30, 2017
n	484	529	2,248
Adjusted HR^a (95% CI)	1	1.25 (1.0–1.57), p = 0.045	0.94 (0.75–1.18), p = 0.577
Age <65 years
n	643	640	2,788
Adjusted HR^a (95% CI)	1	1.31 (1.12–1.54), p = 0.001	0.88 (0.75–1.04), p = 0.130
Age ≥ 65 years
n	352	370	792
Adjusted HR^a (95% CI)	1	1.12 (0.88–1.42), p = 0.352	0.89 (0.68–1.17), p = 0.411
Donor-to-recipient pTLC ratio of ≥1.1
n	336	361	1,064
Adjusted HR^a (95% CI)	1	1.24 (1.0–1.55), p = 0.054	0.85 (0.67–1.08), p = 0.194
Donor-to-recipient pTLC ratio of <1.1
n	659	649	2,516
Adjusted HR^a (95% CI)	1	1.23 (1.04–1.46), p = 0.014	0.92 (0.77–1.09), p = 0.332

Abbreviations: HR, hazard ratio; LAS, lung allocation score; pTLC, predicted lung capacity.

Covariates include age, blood type, ethnicity/race (black, white, Hispanic, other), gender, LAS at time of transplantation, pulmonary hypertension, lung listing preference, donor-to-recipient pTLC ratio (pTLC ratio ≥1.1 or <1.1), and transplantation center.