Table 2. Clinical data according to presence of overweight or obesity. Data expressed as n (%), meanstandard deviation or median (interquartile range).

A two-sided p < 0.05 was considered to be statistically significant and is shown in bold. Within non-statistically significant (ns) cells, only numerical values less than 0.1 are shown. Student’s t test was used to assess differences between normally distributed quantitative variables and Mann-Whitney U test for non-normally distributed variables from two groups and Chi square to assess differences in categorical variables within each row.

	Overweight				Obese				P value obese vs overweight (all)
	All, n = 360	Men, n = 184	Women, n = 176	pc	All, n = 296	Men, n = 132	Women, n = 164	pc
Age (years)	52.78 ± 22.19	53.26 ± 21.66	52.28 ± 22.78	ns	53.29 ± 22.63	56.54 ± 21.69	50.68 ± 23.10	0.027	ns
BMI (kg/m2)	27.51 ± 1.46	27.50 ± 1.44	27.51 ± 1.48	ns	34.98 ± 2.75	35.16 ± 2.73	34.83 ± 2.78	ns	<0.0001
SBP (mmHg)	128.78 ± 11.20	129.77 ± 11.54	127.74 ± 10.77	ns (0.086)	128.91 ± 11.68	128.03 ± 11.41	129.62 ± 11.87	ns	ns
DBP (mmHg)	82.69 ± 6.94	81.89 ± 6.67	83.47 ± 7.13	0.031	82.95 ± 6.83	82.17 ± 6.71	83.57 ± 6.88	ns (0.078)	ns
Prehypertension/hypertension	261 (72.5%)	137 (74.46%)	124 (70.45%)	ns	215 (72.63%)	93 (70.45%)	122 (74.39%)	ns	ns
Prehypertension	95 (28.39%)	42 (22.82%)	53 (30.11%)	ns	81 (27.37%)	39 (29.55%)	42 (25.61%)	ns	ns
Hypertension	166 (46.11%)	95 (51.63%)	71 (40.34%)	0.032	134 (45.27%)	54 (40.91%)	80 (48.78%)	ns	ns
Glycemia (mg/dl)	101.73 ± 18.94	103.37 ± 18.94	100.00 ± 18.83	ns (0.092)	104.10 ± 20.34	106.03 ± 20.69	102.56 ± 19.99	ns	ns
Prediabetes/diabetes	173 (48.05%)	96 (52.17%)	77 (43.75%)	ns	152 (51.35%)	70 (53.03%)	82 (50.0%)	ns	ns
Prediabetes	118 (32.77%)	64 (34.78%)	54 (30.68%)	ns	78 (26.4%)	29 (21.97%)	49 (29.88%)	ns	ns (0.074)
Diabetes	55 (12.28%)	32 (17.4%)	23(13.06%)	ns	74 (25.0%)	41 (31.1%)	33 (20.12%)	0.031	0.002
Albuminuria, mg/24 h	29.94 ± 14.76	29.54 ± 13.35	30.35 ± 16.13	ns	36.85 ± 37.2	35.71 ± 34.59	37.76 ± 39.27	ns	0.001
Albuminuria ≥30 mg/24 h, n (%)	13 (3.61%)	6 (3.26%)	7 (3.98%)	ns	23 (7.77%)	8 (6.06%)	15 (9.15%)	ns	0.020
Urea (mg/dL)	32.70 ± 3.02	32.68 ± 2.98	32.72 ± 3.08	ns	32.47 ± 3.66	32.18 ± 3.64	32.70 ± 3.66	ns	ns
Creatinine (mg/dL)	0.92 ± 0.17	0.98 ± 0.17	0.85 ± 0.15	<0.0001	0.90 ± 0.16	0.96 ± 0.16	0.86 ± 0.15	<0.0001	ns
eGFR (ml/min/1.73 m2)	85.34 ± 20.3	88.28 ± 18.56	82.27 ± 21.66	0.005	84.85 ± 21.1	88.49 ± 19.62	81.93 ± 21.82	0.008	ns
eGFR <60 ml/min/1.73 m2	41 (11.39%)	8 (4.35%)	33 (18.75%)	<0.0001	37 (12.50%)	8 (6.06%)	29 (17.68%)	0.003	ns
eGFR <60 ml/min/1.73 m2 or albuminuria ≥30 mg/24h	51 (14.17%)	13 (7.06%)	38 (21.59%)	<0.0001	55 (18.58%)	17 (12.88%)	38 (23.17%)	0.024	ns
Urate (mg/dl)	4.57 ± 0.97	5.13 ± 0.85	3.99 ± 0.71	<0.0001	4.58 ± 0.94	5.21 ± 0.85	4.07 ± 0.66	<0.0001	ns
Hyperuricemiaa	2 (0.56%)	1 (0.54%)	1 (0.57%)	ns	4 (1.35%)	2 (1.52%)	2 (1.22%)	ns	ns
Cholesterol total (mg/dL)	220 ± 12	220 ± 12	219 ± 12	ns	220 ± 12	220 ± 12	220 ± 12	ns	ns
Triglycerides (mg/dL)	172 ± 14	173 ± 14	171 ± 13	ns	173 ± 14	173 ± 13	173 ± 14	ns	ns
Urine density	1.029 ± 0.003	1.029 ± 0.003	1.028 ± 0.003	0.042	1.029 ± 0.004	1.029 ± 0.004)	1.029 ± 0.004	ns	ns
Urine pH	6.0 (5.0–7.0)	6.0 (5.0–7.0)	6.0 (5.0–7.0)	ns	6.0 (5.0–7.0)	6.0 (5.0–7.0)	6.0 (6.0–7.0)	ns	ns
Urine RBC (n per field)	2.0 (1.0–2.0)	1.0 (0.0–2.0)	2.0 (1.0–3.0)	0.006	1.0 (1.0–3.0)	1.50 (1.0–3.0)	1.0 (0.0–2.0)	ns	ns
Microhematuriab	11 (3.06%)	4 (2.18%)	7 (3.98%)	ns	2 (0.68%)	1 (0.76%)	1 (0.61%)	ns	0.045

Notes.

SBP

systolic blood pressure

DBP

systolic blood pressure

eGFR

estimated glomerular filtration rate

Systolic blood pressure. Fasting glycemia between 100 and 125 mg/dl was considered prediabetes and ≥126 mg/dl diabetes.

^a>6.0 mg/dL in women, >7.0 mg/dL in men.

^b>3 RBC per field.

^cMen vs women within subgroup.