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. 2020 Oct 13;295(50):17349–17364. doi: 10.1074/jbc.REV120.009132

Figure 2.

Figure 2.

Overview of general cellular processing pathways for the membrane transporters. The central and peripheral quality control (QC) pathways are interconnected and work together, shuffling the transporter proteins inside cells and to the plasma membrane, from the ER and Golgi to various intracellular degradation machinery (e.g. endosomes, lysosomes, proteasomes, aggresomes).