Table 2.
Recruiting clinical trials combining immunotherapies with other treatment modalities (https://clinicaltrials.gov) * in adult patients (>18 years of age) with sarcoma.
Trial Registration Number | Title |
---|---|
Immunotherapy with radiation therapy | |
NCT03307616 | Nivolumab with and without ipilimumab and radiation therapy in treating patients with recurrent or resectable undifferentiated pleomorphic sarcoma or dedifferentiated liposarcoma before surgery |
NCT03116529 | Neoadjuvant durvalumab and tremelimumab plus radiation for high-risk STS (NEXIS) |
NCT03463408 | Immunotherapy (ipilimumab and nivolumab) and radiation in resectable STS |
NCT03548428 | Stereotactic body radiation therapy (SBRT) and atezolizumab versus SBRT (STEREOSARC) |
Immunotherapy with chemotherapy | |
NCT03899805 | A phase II study of eribulin and pembrolizumab in STS |
NCT03138161 | SAINT: Trabectedin, ipilimumab and nivolumab as first line treatment for advanced STS |
NCT03074318 | Avelumab and trabectedin in treating patients with liposarcoma or leiomyosarcoma that is metastatic or cannot be removed by surgery |
NCT03719430 | APX005M and doxorubicin in advanced sarcoma |
Immunotherapy with targeted therapy | |
NCT04025931 | A single-arm, open, phase II study of chidamide combined with toripalimab (anti-PD1) in refractory and advanced STS |
NCT03190174 | Nivolumab and ABI-009 (nab-rapamycin) |
* As per 22nd of November 2020.