Table 2.
No-Persistent Airflow Limitation, n = 19 |
Persistent Airflow Limitation, n = 21 |
p-Value | |
---|---|---|---|
Blood Count | |||
Hemoglobin, g/dL | 13.4 (12.9–13.9) | 13.7 (12.6–14.4) | 0.67 |
Red blood cells, 106/µL | 4.62 (4.3–4.84) | 4.71 (4.17–5.16) | 0.71 |
White blood cells, 103/µL | 5.88 (4.95–7.51) | 7.45 (6.51–9.25) | 0.008 |
Neutrophils, 103/µL | 3.5 (2.7–4.2) | 3.54 (2.7–4.2) | 0.73 |
Lymphocytes, 103/µL | 1.9 (1.5–2.4) | 2.2 (1.97–2.6) | 0.13 |
Monocytes, 103/µL | 0.51 (0.48–0.68) | 0.68 (0.53–1.1) | 0.02 |
Blood platelets, 103/µL | 218 (177–246) | 224 (187–294) | 0.26 |
Asthma and Inflammatory Biomarkers in Peripheral Blood | |||
Eosinophilia/µL | 130 (70–290) | 565 (380–1340) | <0.001 |
Immunoglobulin E, IU/mL | 43 (22.7–133) | 152 (32–586) | 0.19 |
C-reactive protein, mg/L | 4.24 (0.45–8.67) | 6.71 (0.58–42) | 0.9 |
Interleukin 6, pg/mL | 0.58 (0.43–1.04) | 1.12 (0.5–3.21) | 0.08 |
Interleukin 10, pg/mL | 0.44 (0.005–0.76) | 0.67 (0.41–1.62) | 0.05 |
Periostin, ng/mL | 0.3 (0.27–0.36) | 0.38 (0.31–0.51) | 0.06 |
A disintegrin and metalloproteinase domain-containing protein 33, ng/mL | 1.2 (0.2–2.29) | 1.76 (1.26–2.77) | 0.11 |
Reticular Basement Membrane Thickness | |||
The thickness of the reticular basement membrane of the bronchial mucosa, µm | 5.96 (5–7.96) | 6.2 (5.24–7.45) | 0.9 |
Bronchoalveolar Lavage Cellularity and Biomarkers | |||
Macrophages, % | 86.8 (74.5–93) | 83 (56.3–91) | 0.47 |
Lymphocytes, % | 7 (4.5–15.5) | 7 (3–10.5) | 0.33 |
Neutrophils, % | 3 (2–4.5) | 4 (2–12.5) | 0.34 |
Eosinophils, % | 0.1 (0–1) | 2.3 (0.5-7) | 0.004 |
Periostin, ng/mL | 0.85 (0.76–0.96) | 0.81 (0.72–0.95) | 0.6 |
Interleukin 6, pg/ml | 0.99 (0.67–1.14) | 0.2 (0.005–0.86) | 0.01 |
Interleukin 10, pg/ml | 0.01 (0.005–0.01) | 0.01 (0.005–0.01) | 0.81 |
Variables are presented as medians and interquartile range.