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. 2021 Jan 20;11:599588. doi: 10.3389/fpsyt.2020.599588

Figure 5.

Figure 5

WKY showed impaired performance in the DNMP task in comparison to SD rats, single administration of ketamine further impaired performance 30 min post-administration but improved performance 24 h post-administration (A) WKY and SD performance in the DNMP 30 min after vehicle administration. (B) WKY 30 min post-administration of ketamine (5 mg/kg s.c.) and SD vehicle 30 min post-administration of vehicle. (C) WKY 24 h post-administration of ketamine (5 mg/kg, s.c.) and SD vehicle 24 h post-administration of vehicle. (D) WKY and SD performance 30 min after vehicle administration, correct responses grouped by short (1–15 s) and long (16–30 s) delay periods. (E) WKY 30 min post-administration of ketamine (5 mg/kg, s.c.) and SD vehicle 30 min post-administration of vehicle, correct responses grouped by short (1–15 s) and long (16–30 s) delay periods. (F) WKY 24 h post-administration of ketamine (5 mg/kg, s.c.) and SD vehicle 24 h post-administration of vehicle, correct responses grouped by short (1–15 s) and long (16–30 s) delay periods. Data are expressed as mean ± SEM, n = 9–10 per group. *p < 0.05, **p < 0.01. WKY, Wistar Kyoto; SD, Sprague Dawley; DNMP, delayed non-match to position task.