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. 2020 Dec 30;58(2):199–210. doi: 10.3892/ijo.2020.5165

Figure 2.

Figure 2

Aspirin causes cell cycle arrest in HuCCT-1 cells. (A) HuCCT-1 cells treated with or without 2.5 mmol/l aspirin were analyzed by flow cytometry to estimate the proportion of cells in each phase of the cell cycle. (B) Graphical representation of the proportion of cells in each phase of the cell cycle. Aspirin blocked the cell cycle at the G/G ** 0 1 phase. P<0.01, vs. the control. (C) Expression of cyclin D1, cyclin E, Cdk2, Rb, and pRb in HuCCT-1 cells 24 and 48 h after aspirin treatment. Rb, retinoblastoma; pRb, phosphorylated Rb.