Table 3.

Brain Regions Significantly Related with Placebo Response in Pediatric Anxiety Disorder (n = 22)

ROIs	Brain regions	Cluster size (voxels)	Peak t value	Peak MNI coordinate
				X	Y	Z
Dynamic FC
Left amygdala	Left IPL	71	4.86	−50	−34	45
	Right insula	59	4.54	36	14	−12
	Right angular	41	5.76	34	−73	33
Right amygdala	Left fusiform	58	6.06	−36	−62	−6
Left dACC	Left angular	56	4.83	−39	−53	33
Right dACC	Left mPFC	49	4.72	−20	14	54
Left VLPFC	Left IPL	51	5.50	−56	−45	33
Static FC
Right amygdala	Left DLPFC	123	5.39	−22	6	51
	Right mPFC	78	3.62	8	11	48
Left dACC	PCC	78	3.74	6	−56	36
Left VLPFC	Right IPL	129	3.85	36	−42	33

AlphaSim corrected, p < 0.05.

ROIs, region of interests; MNI, Montreal Neurological Institute; FC, functional connectivity; DLPFC, dorsolateral prefrontal cortex; mPFC, medial prefrontal cortex; dACC, dorsal anterior cingulate cortex; PCC, posterior cingulate cortex; VLPFC, ventrolateral prefrontal cortex; IPL inferior parietal lobule.