Skip to main content
. 2021 Jan 27;58(3):298–311. doi: 10.3892/ijo.2021.5178

Figure 6.

Figure 6

miR-204-3p inhibits OS cell proliferation, migration and invasion, and promotes OS cell apoptosis by targeting HMGA2. (A) Transfection efficiency of si-HMGA2. (B) Cell Counting Kit-8 assays were performed to assess the effect of miR-204-3p and HMGA2 on HOS and SaOS-2 cell proliferation. Transwell assays were performed to determine the effect of miR-204-3p and HMGA2 on HOS and SaOS-2 cell (C) migration and (D) invasion (scale bar, 500 µm). (E) Flow cytometry was performed to determine the effect of miR-204-3p and HMGA2 on HOS and SaOS-2 cell apoptosis. **P<0.01 vs. si-NC. miR, microRNA; OS, osteosarcoma; si, small interfering RNA; HMGA2, high mobility group A2; NC, negative control; OD, optical density; d, days.