Table 1.
Characteristics of studies reporting on patients with repeat local treatment for recurrent colorectal liver metastases including years of inclusion, study design, number of patients, and age.
| Author | Year | Years of Inclusion |
Number of Patients with Repeat Local Treatment | Median Age in Years (Range) |
Mean Age in Years ± SD |
|---|---|---|---|---|---|
| Adair [45] | 2012 | 1993–2010 | 195 | 63 (24–85) | NR |
| Adam [46] | 2003 | 1984–2000 | 139 (2nd) * 60 (3rd) * |
NR (32–78) NR (33–86) |
56 ± 10 56 ± 10 |
| Andreou [47] | 2011 | 1993–2009 | 43 | 55 (32–74) | NR |
| Brachet [48] | 2009 | 1992–2007 | 62 (2nd) * 15 (3rd) * 2 (4th) * |
NR NR NR |
62.2 ± 9.7 57.9 ± 10.8 54.5 ± 10.6 |
| Butte [49] | 2015 | 1994–2004 | 159 (PST) | 59 (31–81) | 58.1 ± 10.9 |
| Hallet [50] | 2016 | 2006–2013 | 447 | 61.4 (NR) | NR |
| Hashimoto [51] | 2016 | 2000–2012 | 17 | 60 (40–80) | NR |
| Heise [52] | 2017 | 2010–2016 | 38 | 59.1 (NR) | NR ± 12.1 |
| Homayounfar [53] | 2013 | 2001–2011 | 52 | 62.8 (NR) | NR |
| Imai [54] | 2018 | 2000–2016 | 54 | 64 (25–94) a | 63.1 ± 11.0 a |
| Imai [55] | 2019 | 1992–2012 | 29 | 57 (31–82) a | 55.8 ± 9.9 a |
| Ishiguro [56] | 2006 | 1985–2004 | 111 | NR | 59 ± NR |
| Kishi [57] | 2019 | 2000–2015 | 115 | 59 (28–86) | NR |
| Matsuoka [58] | 2019 | 1974–2016 | 59 | NR (25–95) a | 66 ± 11.2 a |
| Neal [59] | 2017 | 2001–2010 | 71 | 64 (26–85) a | 63.4 ± NR a |
| Neeff [60] | 2013 | 1999–2011 | 77 | NR | NR |
| Pessaux [61] | 2006 | 1992–2002 | 42 | NR (34–80) | 63.5 ± NR |
| Valdimarsson [62] | 2019 | 2005–2015 | 82 | 64 (NR) | NR |
| Viganò [63] | 2014 | 1998–2009 | 234 | NR | NR |
| Wicherts [64] | 2013 | 1990–2010 | 263 | NR | 57 ± 11 |
Note: SD = standard deviation; NR = not reported; PST = potential salvage therapy (re-resection of all recurrent disease); * = Rank from total number of hepatectomies; a = age of total population.