Table 2.
Drug | Mechanism | Concentration Range (μM) | Solvent |
---|---|---|---|
Carboplatin | Intra- and inter-strand cross-linkage of DNA | 500–0 | MQ + 0.01% Tween |
Paclitaxel | Microtubule stabilizer, induces mitotic arrest | 50–0 | DMSO |
Tamoxifen | Estrogen receptor blocker | 20–0 | DMSO |
Letrozole | Aromatase inhibitor | 50–0 | DMSO |
Fulvestrant | Estrogen receptor blocker | 100–0 | DMSO |
Ulipristal | Progesterone receptor blocker | 50–0 | DMSO |
Anastrozole | Aromatase inhibitor | 200–0 | DMSO |
Everolimus | mTOR inhibitor | 50–0 | DMSO |
Alpelisib | PI3K inhibitor | 100–0 | DMSO |
Dasatinib | Tyrosin kinase inhibitor | 20–0 | DMSO |
6-THIO-2dG | Telomerase blocker | 50–0 | DMSO |
All drug compounds were obtained from Sigma-Aldrich.