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. 2021 Jan 20;13(3):380. doi: 10.3390/cancers13030380

Table 2.

Multivariate Cox regression analysis of factors associated with overall survival.

Prognostic Factors HR 95% CI p-Value
Age (per 1-year increase) 1.04 1.00–1.08 0.04 *
Sex (female vs. male) 1.22 0.55–2.72 0.62
Histology
(adenocarcinoma vs. non-adenocarcinoma)
0.38 0.18–0.83 0.02 *
GPA score (high vs. low) 0.21 0.09–0.45 <0.001 *
Integrin β3 (per 1-ng/mL increase) 1.25 1.04–1.49 0.02 *
Integrin β6 (per 1-ng/mL increase) 0.90 0.68–1.18 0.44

Abbreviations: HR, hazard ratio; CI, confidence interval; vs., versus; GPA, graded prognostic assessment. Asterisk denotes significance.