Upon 36-h starvation, Fam134b−/− mice avoided starvation induced hypocalcemia as tested by serum calcium levels. The animals tested for serum electrolyte levels were an average of 18 mo old, and the groups were as follows: Fam134b+/+-ad libitum (WT-AL), n = 6 (4 male, 2 female); Fam134b+/+-starvation (WT-ST), n = 6 (4 male, 2 female); Fam134b−/−-ad libitum (KO-AL), n = 11 (8 male, 3 female); Fam134b−/−-starvation (KO-ST), n = 13, (9 male, 4 female). Mann-Whitney nonparametric test results are represented as means ± SD. P < 0.05 was considered as significant. Nonsignificant results are not indicated.