| 5-HTRs | serotonin receptors |
| CNS | central nervous system |
| GPCRs | G protein-coupled receptors |
| TMDs | transmembrane domains |
| ICL | intracellular loop |
| ECL | extracellular loop |
| SDM | site-directed mutagenesis |
| Tc | Tanimoto coefficient |
| SIFt | Structural Interaction Fingerprint |