(a–d) Quantification of circulating peripheral blood mononuclear cells, including CD3+ T cells (a), CD4+ helper T cells and CD8+ cytotoxic T cells (b), CD11b/c+ myeloid cells (c) and CD45R+ B cells (d). (e,f) Splenic T cells stained with anti-CD3 (e) quantified in panel (f). Recipient groups of SSCD247−/− rats included naive control rats (Control; n = 7), rats receiving a splenocyte transfer from donor rats maintained on a low-salt diet (LSS; n = 11) and rats receiving splenocyte transfer from donor rats maintained on a high-salt diet (HSS; n = 13). **P < 0.01 and ***P < 0.001 versus Control. One-way ANOVA with the Holm–Sidak post hoc test was used in panels (c,d), and the P-value for the effect of treatment is reported in each graph