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. 2021 Feb 5;180(6):1675–1692. doi: 10.1007/s00431-020-03898-9

Table 3.

ECMO Criteria for CDH patients: a comparison between ELSO and CDH Euro Consortium Consensus indications

ELSO* CDH EURO Consortium Consensus°

1. Inability to maintain preductal saturations > 85% or postductal saturations > 70%;

2. Respiratory acidosis with pH < 7.15 despite optimal ventilator management;

3. PIP > 28 cm H2O or MAP > 17 cm H2O is required to achieve saturation > 85%;

4. Refractory metabolic acidosis;

5. PaO2 < 40 for 4 h on FiO2 1.00;

6. Hypotension refractory to vasopressors;

7. OI > 40 for 4 h.

1. Inability to maintain preductal saturations > 85% or postductal saturations > 70%;

2. Increased PaCO2 and respiratory acidosis with pH < 7.15 despite optimization of ventilator management;

3. PIP > 28 cm H2O or MAP > 17 cm H2O is required to achieve saturation > 85%;

4. Inadequate oxygen delivery with metabolic acidosis as measured by elevated lactate ≥ 5 mmol/L and pH < 7.15;

5. Systemic hypotension, resistant to fluid and inotropic therapy, resulting in urine output < 0.5 mL/kg/h for at least 12–24 h;

6. OI ≥ 40 present for at least 3 h.

*Adapted from the ELSO Guidelines for neonatal respiratory failure 2017 [22]

°Adapted from the CDH EURO Consortium Consensus – 2015 Update [52]

PIP, peak inspiratory pressure; MAP, mean airway pressure; OI, oxygenation index