FIG. 11.

Wax-printed 3D microfluidic devices. (a) Schematic for the fabrication of microfluidic devices of any size and configuration, which requires paper, a wax printer, scissors, and spray adhesive. This technique enables a high throughput of devices by assembling entire sheets of patterned paper with adhesive. (b) 8 cm wide × 8 cm long × 0.1 cm thick microfluidic device, which distributes four different samples from the top of the device into (c) the bottom of the device, which has separate grids containing 256 output regions. This device has six layers and the four samples (1 ml each) filled the hydrophilic regions on the top of the device.¹³⁵ Reproduced with permission from Lewis et al., Lab Chip 12, 2630–2633 (2012). Copyright 2012 Royal Society of Chemistry.