Low-cost photolithography and embossing technique for microfluidic devices. (a) and (b) Photolithographically patterned Parafilm where the photosensitive blue ink painted Parafilm and a transparent film with the desired pattern are exposed to a UV light. (c) Embossing of Parafilm: filter paper, photolithography patterned Parafilm, and aluminum foil are assembled and sandwich between two glass slides. (d) The sandwich is pressed together and heated to 120 °C for several minutes. (e) and (f) Filter paper is removed from the assembly, and the finished patterned Parafilm is complete.143 Reproduced with permission from Yu et al., Lab Chip 15, 1642–1645 (2015). Copyright 2015 Royal Society of Chemistry.