Skip to main content
. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Cancer Immunol Res. 2020 Dec 22;9(2):239–252. doi: 10.1158/2326-6066.CIR-20-0638

Figure 2. Combination of Ad-CEA+N-803 temporally upregulates OX40 and GITR expression in CD4+ and CD8+ splenocytes.

Figure 2.

Naive female C57BL/6-CEA-Tg mice were injected concurrently with Ad-CEA (subcutaneous, s.c.) and N-803 (s.c.). Spleens were collected 0, 8, 18, 24, 48, and 72 hours after the injection. Frequency, total cell number, and mean fluorescence intensity (MFI) of GITR and OX40 expression on (A-B) CD4+ and (C-D) CD8+ splenocytes were analyzed via flow cytometry. Error bars represent mean±SEM. These studies were repeated 3–4 times with similar results.