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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Prog Retin Eye Res. 2020 Aug 6;81:100886. doi: 10.1016/j.preteyeres.2020.100886

Figure 4: Four different phases of oligodendrocyte (OL) maturation in the oligodendroglial lineage: OPC, pre-OLs, immature OLs and mature OLs.

Figure 4:

These phases were established based on the increasingly complex morphology and the expression pattern of well-defined markers. CNPase, 2′,3′-cyclic nucleotide 3′-phosphodiesterase; FABP, fatty-acid-binding proteins; GalC, galactocerebroside C; MAG, myelin associated glycoprotein; MBP, myelin basic protein; MOG, myelin OL glycoprotein;Olig1/2 two basic helix-loop-helix transcription factors; PDGF-Rα, platelet-derived growth factor; PLP, proteolipid protein; PSA-NCAM, polysialic acid-neural cell adhesion molecule.